A minor clarification; Andrew I think you mean “Trim the SSD” which is something completely different than a Defrag. Typically you don't want to defrag a SSD as such operation will shorten its lifespan, cost unnecessary write cycles, and doesn't add any value to its performance due to how a SSD actually works at low level. All modern O/S will disable the defrag option for a SSD so it’s the Trim* feature you want and need. The Trim command basically tells the drive that a memory block is available and can be zero'd out while the drive is still being used by the system. This way the write performance will be on top all the time. A drive without Trim support will after some time usually have a huge write performance hit, usually in the range of 50% to 60% less write performance based on my own experience, but only during the second and forward write cycles of that specific block. Of course Trim must be present in both the actual drive and the operating system or by using a 3rd party tool. For instance Intel has a tool for their Trim supported drives if you are running XP or Vista as those systems don't support Trim natively.
*http://en.wikipedia.org/wiki/TRIM
//Thomas
This post was written on a machine with a SSD and Trim support :-)